Myth or truth? AS Disable Seniors Only Say no to plagiarism. Get a tailor-made essay on "Why Violent Video Games Shouldn't Be Banned"? Get an original essay Again, it's folklore. It happens most often in white men and their ages range from twenty to forty, although this can also occur in children. It is rare and rarely begins after age 45. Nearly 90% of individuals suffer from this which creates a “genetic marker” – a protein known as HLA-B27. But having the receptor doesn't mean you will definitely acquire AS: fewer than 5% of people with HLA-B27 acquire AS. Two new genes have been discovered, both IL23R and ERAP1, which may also pose an inherited risk for AS. Although it is a form of arthritis, this only affects around 1 in 1000 individuals. The specific cause of AS is not understood, however there appears to be a hereditary link. Myth or truth? NSAIDs have no alternative. One study demonstrated that anti-TNF agents improve symptoms in the treatment of AS. Those who do not respond to NSAIDs, biologics, or tumor necrosis factor (TNF)-alpha inhibitors (TNF blockers), may be an integral part for them. TNF blockers can cause pain and swelling in the lower spine; they may not even see the progress. TNF blockers could be used together with NSAIDs to treat symptoms. FDA-approved biologics for spondylitis include: Humira (adalimumab) and its biosimilars Amjevita (adalimumab-atto) approved in September 2016, also Cyltezo (adalimumab-adbm), approved in August 2017 Cimzia (certolizumab) Enbrel (etanercept) and the own biosimilar Erelzi (etanercept-szzs)Remicade (infliximab) and its own biosimilars Inflectra (infliximab-dyyb), Renflexis (infliximab-abda) or Ixifi (infliximab-qbtx)Simponi (golimumab)They are contrasted in the clinic or administered by home injection. Few people suffering from this may have to deal with situations up to 14 days, however, for many others it may take several weeks. Myth or truth? Drugs are the only way to cure ASThis ad is truly folkloric. Combining an AS support team can offer benefits. Although medications are just one element, they are not used independently. The objectives of the therapy are four: Reduce swelling and joint pain weakens the development of the disorder avoid joint destruction, such as kyphosis maintain posture and daily work/life operate the remedy for AS involves a multi-step strategy: medicine , physical treatment or exercise, use of heat/cold for muscle relaxation and to relieve joint pain. Myth or truth? AS leads to critical disordersFolklore. It is not a life-threatening disease, and in fact, many people have the ability to work and function normally throughout the day. Not all those who suffer from AS present acute disorders or physical handicaps: the course of the disease is changeable and differs considerably from one victim to another. Typically, AS is characterized by debilitating episodes accompanied by remissions, periods in which pain occurs. Studies show that those who suffer from this disorder in later life may be more vulnerable to serious joint injuries. Furthermore, smokers are four times less likely to suffer harm than non-smokers. For acute AS or other joint problems, you may rarely need surgery or joint replacement. Myth or truth? AS only disables BackThis is folklore. The term spondylitis refers to swelling of the spine; ankylosis means combination of two bones into one. AS is a kind of arthritisinflammatory and debilitating disease that damages the lower spine and joints. But they can also belong to other joints such as the shoulders, knee, hips, ribs, heels and smaller joints in the legs or arms. The eyes may be affected (uveitis) and, rarely, the heart and lungs. The joints between the vertebrae and the anus finally strengthen each other. This can limit movement and lead to acute discomfort. Individuals with acute AS might disappear invisibly due to the set position of the spine being called kyphosis. Erectile kyphosis. Myth or truth? Individuals with AS must be prevented from exercising. This too is a myth. A defined strategy of physical therapy and personalized exercise is very important for all those suffering from AS. Back stiffness, especially in the morning, is a quality of AS that often improves with action. Individuals who have this disease may worsen if they do not exercise regularly. The doctor may refer the individual to a therapist who will create a strategy of stretching, deep breathing, and range of motion exercises. Hydrotherapy could also work. Physical treatment can help keep your spine flexible, avoid stooping, make daily activities easier, and reduce the chance of acute pain or further damage. Myth or truth? Analysis of ankylosing spondylitis requires many testsThis is not folklore. Identification is usually quite simple. A rheumatologist, a doctor who specializes in arthritis, will also likely make the initial identification. An x-ray or MRI can reveal if there is inflammation of the sacroiliac joint. Your healthcare provider may also perform a blood test to check for genetic markers; the medical history and symptoms also help in carrying out the analysis. Experience swelling or discomfort in the lower back for a period of 3 weeks, which is enhanced by exercise, but is not relieved by rest. Limitations of movement of the lumbar spine during flexion. Restrictions on chest growth after breathing. Myth or truth? There is little I can do to help myself. This is not the truth. Patients who can participate in an active lifestyle, maintain a regular exercise regime along with load, prevent smoking and also keep appointments and therapies from the office will get a better effect. Studies have shown that a diet rich in omega-3 fatty acids could reduce joint inflammation in rheumatoid arthritis sufferers, and there is evidence that it could be beneficial in AS. A firm mattress could help reduce morning swelling. Some people prefer swimming to exercise because it is less harmful to the joints. Myth or truth? Drug treatment for ankylosing spondylitis is always expensive. This too is folklore; the first drug treatment could be economical. Drug therapy with anti-swelling NSAIDs or analgesics, such as:§ naproxen (Aleve)§ indomethacin§ aspirin (Advil)§ paracetamol (Tylenol)§ celecoxib (Celebrex)§ diclofenac (Cataflam) The above-mentioned are usually the first drugs used for AS therapy. These medications are readily available both over-the-counter (OTC) and by prescription, and many are available in inexpensive generics. But NSAIDs could be related to serious side effects such as stomach upset, heart problems, and stroke patients should review these side effects with their doctor, especially with long-term chronic use of NSAIDs. Myth or truth? Ankylosing spondylitis is easily treatable. Once again the myth. There is no cure for AS; however, there are FDA-approved medications that canreduce AS symptoms and help manage pain. AS is an autoimmune disease that occurs when the immune system mistakenly attacks the human body's own tissues. NSAIDs are helpful for pain, and research reveals that TNF blockers may prevent or stop the development of AS disease. AS is characterized by intense, debilitating flares of spinal discomfort accompanied by a period of remission in which signs worsen. In some patients, the pain may occur elsewhere, such as in the shoulders, ribs, hips, and small joints in the feet and hands. The pain may worsen throughout the day and decrease throughout the day and even with exercise. In 2016, secukinumab (Consentyx), the first in a new class of drugs known as interleukin-17A (IL-17A) inhibitors, was approved by the FDA to treat AS. Consentyx considerably reduces the symptoms and signs of AS and increases overall freedom. Myth or truth? Injections of TNF blockers immediately cause skin reactions Certainly folklore. In fact, the most common side effect seen with all TNF blockers is skin reactions at the injection site. A localized rash, burning, or itching may occur and may last up to a week. Also, patients on TNF blockers should talk to their doctor before getting anything "live," as TNF blockers can make the vaccine less effective. Approximately 10 to 20% of individuals (10 to 20 in 100) may experience injection site reactions, which are normally described as moderate. But if the response persists after a week, contact your doctor. Myth or truth? TNF blocker side effects are extremely dangerous, not necessarily. As with most medications, TNF blockers have critical side effects. A high frequency of diseases, such as tuberculosis (TB) or bacterial diseases, may occur. But, along with TNF blockers, most of these very serious side effects are also quite rare. But, before starting treatment with TNF blockers, a tuberculosis evaluation is performed to rule out active disease. Furthermore, a very rare side effect is the increased frequency of particular cancers, such as leukemia (blood cancer), lymphoma (cardiovascular cancer) or non-melanoma skin cancers. Infliximab is also linked to a severe allergic response. Myth or truth? If TNF Blockers Don't Work, There Are No Other Bad Choices Long-term chronic use of corticosteroids is discouraged due to unwanted side effects. Oral corticosteroid use may also be discouraged. Sulfasalazine, an oral disease-modifying drug frequently used in rheumatoid arthritis, which could be used in patients with AS who have symptoms in different regions beyond just the spine. TNF blockers are effective for all individuals with AS, but there are still other options for patients who do not respond or cannot use them. Local corticosteroid injections, such as methylprednisolone (Solu-Medrol), may be used intermittently if there is evidence of local joint swelling. In general, opioid painkillers should be avoided due to side effects and addiction. Approximately 20%-40% of patients do not respond well to standard maintenance biologics and there are now several choices. In 2016, the FDA accepted Cosentyx (secukinumab) to treat AS, offering an entirely new type of treatment choice. Myth or truth? TNF blockers may not help slow damage in AS This is a controversial topic. The researchers say the therapy must.