Company or enterprise that operates in multiple countries, generally defined as an enterprise that has 25% or more of its production capacity located outside its home country. The four largest multinationals in the world in 2000 were Exxon Mobil, Wal-Mart Stores, General Motors and Ford Motor: their combined revenues were higher than the combined gross national product of all African countries. In 2000, 22 multinational corporations made profits of more than $6 billion, while Exxon Mobil made profits of $17.7 billion, a 124 percent increase from the previous year. The value of mergers and acquisitions in 2000 was estimated at $3.2 trillion, the most notable being Pfizer with Warner-Lambert in a $116 billion deal and Glaxo Wellcome's purchase of SmithKline Beecham for $76 billion (to create GlaxoSmithKline). quarters as a threat to individual national sovereignty and as the use of undue influence to ensure favorable operating conditions.